Leonardo#
A toolset to remove sample-induced aberrations in light sheet microscopy images
Leonardo is an AI-empowered image processing toolbox that is able to resolve sample-induced
aberrations for light-sheet fluorescence microscopy: (1) Leonardo-DeStripe removes the stripe artifacts caused by light absorption;
(2) Leonardo-Fuse reconstructs one single high-quality image from dual-sided illumination and/or dual-sided detection while
eliminating optical distortions (ghosts) caused by light refraction.
Manuscript#
Preprint is available here.
Installation
How to install Leonardo.
Tutorials
Get started with example notebooks and video tutorials.
Tuning Guidance
Parameter tuning and validation workflow.
API Reference
Detailed descriptions of Leonardo modules: DeStripe, Fuse_illu, Fuse_det.